Color Atlas of Dermatopathology (Dermatology: Clinical & - download pdf or read online

By Jane M. Grant-Kels

ISBN-10: 0849337941

ISBN-13: 9780849337949

This impressive dermatopathology atlas emphasizes the correlation of pathological findings with medical shows and offers a reader-friendly method of the analysis and interpretation of epidermis biopsy effects. With an abundance of colour scientific and histologic pictures, and outlines of various dermatological ailments and prerequisites, this resource is a must have for someone getting ready for dermatology or pathology board checks, or for these wanting a powerful realizing of the medical or pathological shows of disorder.

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Additional info for Color Atlas of Dermatopathology (Dermatology: Clinical & Basic Science)

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10C). Keratinocytic atypia is minimal or absent Differential Diagnosis: Lichen Planus-Like Keratosis Parakeratosis is commonly present and may be prominent Histology: B B Present as a solitary, violaceous, slightly scaly papule, or plaque of apparently acute onset, usually on the upper trunk or proximal upper extremities in adults between the ages 40 and 70 Minimal-to-absent keratinocytic atypia Lichen Planus Parakeratosis is not a feature — Lichenoid Solar Keratosis — Prominent keratinocytic atypia Pathophysiology: B Lichen planus-like keratosis is thought to represent the spontaneous involution of a solar lentigo, large cell acanthoma, or reticulated seborrheic keratosis via a cell-mediated immunologic reaction Chapter 3: Interface Dermatitis References: 1.

Arch Dermatol 1982; 118:478. 2. Dereure O, Levi E, Kadin ME. T-cell clonality in pityriasis lichenoides et varioliformis acuta. A heteroduplex analysis of 20 cases. Arch Dermatol 2000; 136:1483–1486. Clinical Feature The offending drug acts as a hapten which binds to a protein in basal keratinocytes or in melanocytes within the basal layer of the epidermis The hapten– host protein complex appears to activate T lymphocytes, thereby inciting a cytotoxic immune reaction that may be antibody-mediated The site-specificity and sharp circumscription of the clinical lesions may be due to localized expression on keratinocytes of a cell-adhesion antigen (CD54, ICAM-1) involved in the adherence between keratinocytes and lymphocytes References: 1.

Lichen striatus. A Blaschko linear acquired inflammatory skin eruption. J Am Acad Dermatol 1991; 25(4):637– 642. 2. Gianotti R, Restano L, Grimalt R, et al. Lichen striatus—a chameleon: an histopathological and immunohistological study of forty-one cases. J Cutan Pathol 1995; 22(1):18– 22. 3. Tosti A, Peluso AM, Misciali C, Cameli N. Nail lichen striatus: clinical features and long-term follow-up of five patients. J Am Acad Dermatol 1997; 36(6 Pt 1):908– 913. Treponema pallidum, a microaerophilic spirochete, usually acquired through sexual contact, penetrates intact mucous membranes or microabrasions in the skin and rapidly enters the lymphatics and blood to cause systemic infection.

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Color Atlas of Dermatopathology (Dermatology: Clinical & Basic Science) by Jane M. Grant-Kels

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