By Marcel F. Jonkman
This e-book presents compulsory examine fabric on classes on autoimmune bullous ailments. citizens and researchers in dermatology and adjoining disciplines can use the publication as a brief reference consultant whilst facing those sufferers. The publication comprises protocols and follows overseas guidelines. presently there isn't any speedy primer on Autoimmune Bullous ailments for dermatologists who desire to research the subtleties of analysis and administration of this staff of mucocutaneous illnesses. for the reason that mucous membranes also are incorporated the subsequent clinical disciplines should be too: oral medication and stomatology, ENT, ophthalmology, gynaecology, gastro-enterology. the guts for Blistering illnesses in Groningen has equipped because the yr 2000 an annual path on Bullous ailments for dermatologists and pathologists. the workers is chosen from the college. The direction is interactive and problem-oriented. The proposed booklet could characterize the documented useful wisdom of the employees on those illnesses. the knowledge might be transparent and functional with examples and questions for self-assessment.
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Extra info for Autoimmune Bullous Diseases: Text and Review
The liquid contents of a serous vesicle is (a) Transparent (b) Opaque (c) Purulent (d) Leaking 2. Intentional epidermal detachment from within the lesion extending into normal-appearing skin is called (a) Nikolsky’s sign I (b) Nikolsky’s sign II (c) Asboe-Hansen’s sign (d) Sheklakov’s sign 3. Synonym to Nikolsky’s sign I is (a) Marginal Nikolsky’s sign (b) Normal Nikolsky’s sign (c) Indirect Nikolsky’s sign (d) Pseudo-Nikolsky’s sign 4. The beginning of the consolidation phase in BP is the moment when reached (a) Control of disease activity (b) Partial remission on minimal therapy (c) Partial remission off therapy (d) Complete remission on minimal therapy 5.
No? at least two > 2cm and not > 6 cm? no? yes? yes? at least one > 16 cm or entire area? yes? Score 10 Score 2 yes? no? at least one > 6 cm? Score 5 yes? no? Score 3 Mucosa erosions, blistersat entire area? yes? Score 10 yes? Score 1 no? 1 lesion? no? 2 or 3 lesions? yes? no? Score 5 skull erosions, blisters, new yes? lesions? no? Score 0 yes? Score 5 no? more than 3 lesions? yes? two lesions > 2 cm? Score 2 affacts whole skull? yes? Score 4 yes? Score 10 no? 2 quadrants? no? at least 1 lesion > 6 cm?
U-serrated immunodeposition pattern differentiates type VII collagen targeting bullous diseases from other subepidermal bullous autoimmune diseases. Br J Dermatol. 2004;151:112–8. 10. van der Meer JB. Granular deposits of immunoglobulins in the skin of patients with dermatitis herpetiformis. An immunofluorescent study. Br J Dermatol. 1969;81:493–503. H. Diercks and Hendri H. Pas Abstract The purpose of indirect immunofluorescence microscopy is to detect circulating antibodies in patient’s serum.
Autoimmune Bullous Diseases: Text and Review by Marcel F. Jonkman